Berberine
The alkaloid at the centre of the blend, studied for how cells take glucose in.
Fourteen ingredients in a 500 mg proprietary formulation. One page each, with an evidence grade on every one.
The alkaloid at the centre of the blend, studied for how cells take glucose in.
The kitchen spice with the longest run of human trials behind it.
Called gurmar, sugar destroyer, for what it does to sweet taste on the tongue.
A Philippine tree leaf carrying corosolic acid, drunk as tea long before capsules.
A vegetable eaten daily across Asia, bitter enough that nobody eats it by accident.
A compound your own cells make, active in both water and fat.

An essential trace mineral with a published daily intake and a settled role.
Vitamin B7, the cofactor five carboxylase enzymes cannot work without.
The leaf silkworms live on, carrying a sugar-shaped molecule called DNJ.
The rhizome behind curry colour and one of the most studied plant compounds alive.
Not a berry at all but a cone, and the reason gin tastes the way it does.
A root crop grown higher up a mountain than almost any other food plant.
The Ningxia berry that carries zeaxanthin in unusually large amounts.
Fifty times sweeter than sugar by weight, and a digestive herb for millennia.
Other ingredients: vegetable cellulose (capsule), rice flour and magnesium stearate.
Order GlycoAidIngredients on a supplement label are listed in descending order by weight. On this bottle that means Berberine carries more of the 500 mg than anything below it and licorice root carries the least. That is the entire amount of information the ordering gives you. It cannot tell you whether the first name is 300 mg or 60 mg.
Everything else on this page is an attempt to make that limitation useful rather than to talk around it.
Every ingredient page carries one of four grades. They describe the research behind the ingredient, not behind this product, and they are not averaged into a single number anywhere on this site.
| Ingredient | Grade | What that means |
|---|---|---|
| Berberine | Large | Many controlled human trials |
| Cinnamon Bark | Large | Many controlled human trials |
| Gymnema Sylvestre | Moderate | Several small human studies |
| Banaba Leaf | Moderate | Several small human studies |
| Bitter Melon | Moderate | Several small human studies |
| Alpha-Lipoic Acid | Large | Many controlled human trials |
| Chromium | Large | Many controlled human trials |
| Biotin | Settled | An established nutritional role |
| White Mulberry Leaf | Moderate | Several small human studies |
| Turmeric Root | Large | Many controlled human trials |
| Juniper Berry | Small | Long traditional use, limited modern trials |
| Maca Root | Small | Long traditional use, limited modern trials |
| Goji Berry | Small | Long traditional use, limited modern trials |
| Licorice Root | Moderate | Several small human studies |
Grouped by what they are actually doing, the panel reads more clearly. Glucose uptake and insulin sensitivity: Berberine, alpha-lipoic acid and Chromium. Carbohydrate absorption and sweet taste: gymnema, white mulberry and banaba leaf. Antioxidant support: turmeric, goji berry and again alpha-lipoic acid. Traditional-use ingredients: maca, juniper and licorice, with bitter melon and cinnamon bark alongside them.
Two names on this panel come up more than the rest. Berberine carries the largest research base here and leads the label, and chromium is the one ingredient with an established nutritional role rather than a contested one. Both have longer pieces in the reading room.
Research on these ingredients was done at specific doses, mostly on one ingredient at a time. A proprietary blend declares one combined weight, so no trial can be mapped onto this capsule directly. That is the single most important thing to understand about this label and it is why it appears on the homepage rather than in a footnote.
A 500 mg proprietary formulation taken once a day with a meal, and sixty days to decide what you think of it.
